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A new study has found that drinking alcohol primes certain areas of our brain to learn and remember better.
Neurobiologist Hitoshi Morikawa said the common view that drinking is bad for learning and memory isn’t wrong, but it highlights only one side of what ethanol consumption does to the brain.
“Usually, when we talk about learning and memory, we’re talking about conscious memory,” Morikawa said.
“Alcohol diminishes our ability to hold on to pieces of information like your colleague’s name, or the definition of a word, or where you parked your car this morning.
“But our subconscious is learning and remembering too, and alcohol may actually increase our capacity to learn, or ‘conditionability’, at that level,” Morikawa stated.
Morikawa’s study, which found that repeated ethanol exposure enhances synaptic plasticity in a key area in the brain, is further evidence toward an emerging consensus in the neuroscience community that drug and alcohol addiction is fundamentally a learning and memory disorder.
When we drink alcohol (or shoot up heroin, or snort cocaine, or take methamphetamines), our subconscious is learning to consume more. But it doesn’t stop there.
We become more receptive to forming subconscious memories and habits with respect to food, music, even people and social situations.
Morikawa said in an important sense, alcoholics aren’t addicted to the experience of pleasure or relief they get from drinking alcohol.
They’re addicted to the constellation of environmental, behavioural and physiological cues that are reinforced when alcohol triggers the release of dopamine in the brain.
“People commonly think of dopamine as a happy transmitter, or a pleasure transmitter, but more accurately it’s a learning transmitter. It strengthens those synapses that are active when dopamine is released,” Morikawa said.
Alcohol, in this model, is the enabler. It hijacks the dopaminergic system, and it tells our brain that what we’re doing at that moment is rewarding and thus worth repeating.
Among the things we learn is that drinking alcohol is rewarding. We also learn that going to the bar, chatting with friends, eating certain foods and listening to certain kinds of music are rewarding.
The more often we do these things while drinking, and the more dopamine that gets released, the more “potentiated” the various synapses become and the more we crave the set of experiences and associations that orbit around the alcohol use.
Morikawa’s long-term hope is that by understanding the neurobiological underpinnings of addiction better, he can develop anti-addiction drugs that would weaken, rather than strengthen, the key synapses.
And if he can do that, he would be able to erase the subconscious memory of addiction.
“We’re talking about de-wiring things. It’s kind of scary because it has the potential to be a mind controlling substance. Our goal, though, is to reverse the mind controlling aspects of addictive drugs,” he stated.
The findings were published last month in The Journal of Neuroscience.
THAINDIAN
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